Title : Caspases 3 and 9 are translocated to the cytoskeleton and activated by thrombin in human platelets. Evidence for the involvement of PKC and the actin filament polymerization.

Pub. Date : 2006 Aug

PMID : 16300929






1 Functional Relationships(s)
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1 Inhibition of actin polymerization by cytochalasin D inhibits translocation and activation of both caspases, suggesting that thrombin stimulates caspase 3 and 9 activation and association with the reorganizing actin cytoskeleton. Cytochalasin D coagulation factor II, thrombin Homo sapiens