Title : Cytotoxic and cytoprotective actions of O2- and NO (ONOO-) are determined both by cellular GSH level and HO activity in macrophages.

Pub. Date : 2005

PMID : 16291250






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, in cells surviving the toxicity caused by lower doses of O2-, NO, or ONOO-, the depleted intracellular GSH level was replenished, and HO-1 expression was increased, but not when they were coexposed to an inhibitor of HO-1 activity. Oxygen heme oxygenase 1 Homo sapiens
2 However, in cells surviving the toxicity caused by lower doses of O2-, NO, or ONOO-, the depleted intracellular GSH level was replenished, and HO-1 expression was increased, but not when they were coexposed to an inhibitor of HO-1 activity. Oxygen heme oxygenase 1 Homo sapiens
3 Thus, the dichotomous cytotoxic or cytoprotective effects of O2-, NO, or ONOO- in macrophages are determined both by cellular GSH level and by HO-1 activity. Oxygen heme oxygenase 1 Homo sapiens