Pub. Date : 2006 May
PMID : 16289596
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 2 | LPA is well known to induce phosphorylation of the epidermal growth factor receptor (EGFR), which is termed transactivation, in some cell types. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 3 | LPA is well known to induce phosphorylation of the epidermal growth factor receptor (EGFR), which is termed transactivation, in some cell types. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 4 | In this study, we investigated the contribution of EGFR transactivation in LPA-induced responses in colon cancer DLD1 cells. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 5 | MATERIALS AND METHODS: Immunoprecipitation was performed to investigate whether LPA induced EGFR phosphorylation. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 6 | RESULTS: Immunoprecipitation analysis revealed that LPA induced a significant level of tyrosine phosphorylation of EGFR in DLD1 cells. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 7 | The LPA-induced phosphorylation of EGFR was almost completely abrogated by either AG1478 or GM6001. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |