Title : Molecular cloning, functional characterization of the porcine transient receptor potential V1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1.

Pub. Date : 2005 Dec 19

PMID : 16288992






2 Functional Relationships(s)
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1 The various TRPV1 agonists activated pTRPV1 in a dose-dependent manner in the order of potency of resiniferatoxin (RTX) > olvanil > capsaicin > phorbol 12-phenylacetate 13-acetate 20-homovanillate (PPAHV), phorbol 12,13-dinonanoate 20-homovanillate (PDNHV). Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens
2 TRPV1 antagonists, iodoRTX, ruthenium red and capsazepine suppressed capsaicin-induced responses. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens