Title : Inactivation of Id-1 in prostate cancer cells: A potential therapeutic target in inducing chemosensitization to taxol through activation of JNK pathway.

Pub. Date : 2006 Apr 15

PMID : 16287090






4 Functional Relationships(s)
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1 Inactivation of Id-1 in prostate cancer cells: A potential therapeutic target in inducing chemosensitization to taxol through activation of JNK pathway. Paclitaxel mitogen-activated protein kinase 8 Homo sapiens
2 Furthermore, c-Jun N-terminal kinase (JNK), one of the common pathways responsible for taxol-induced apoptosis, was also activated in the si-Id-1 transfected cells. Paclitaxel mitogen-activated protein kinase 8 Homo sapiens
3 Furthermore, c-Jun N-terminal kinase (JNK), one of the common pathways responsible for taxol-induced apoptosis, was also activated in the si-Id-1 transfected cells. Paclitaxel mitogen-activated protein kinase 8 Homo sapiens
4 Inhibition of JNK activity by a specific inhibitor, SP600125, blocked the si-Id-1-induced sensitivity to taxol. Paclitaxel mitogen-activated protein kinase 8 Homo sapiens