Pub. Date : 2006 Apr 15
PMID : 16287090
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Inactivation of Id-1 in prostate cancer cells: A potential therapeutic target in inducing chemosensitization to taxol through activation of JNK pathway. | Paclitaxel | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Furthermore, c-Jun N-terminal kinase (JNK), one of the common pathways responsible for taxol-induced apoptosis, was also activated in the si-Id-1 transfected cells. | Paclitaxel | mitogen-activated protein kinase 8 | Homo sapiens |
3 | Furthermore, c-Jun N-terminal kinase (JNK), one of the common pathways responsible for taxol-induced apoptosis, was also activated in the si-Id-1 transfected cells. | Paclitaxel | mitogen-activated protein kinase 8 | Homo sapiens |
4 | Inhibition of JNK activity by a specific inhibitor, SP600125, blocked the si-Id-1-induced sensitivity to taxol. | Paclitaxel | mitogen-activated protein kinase 8 | Homo sapiens |