Title : Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity.

Pub. Date : 2005 Nov 2

PMID : 16280976






2 Functional Relationships(s)
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1 PURPOSE: Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats. Methimazole insulin-like growth factor 1 Rattus norvegicus
2 PURPOSE: Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats. Methimazole insulin-like growth factor 1 Rattus norvegicus