Title : Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b.

Pub. Date : 2005

PMID : 16277680






1 Functional Relationships(s)
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1 In addition, inhibition of Cyp7b mRNA expression and activity was observed with SN50, PSI and SP600125, suggesting that NF-kappaB and AP-1 induce Cyp7b transcription. pyrazolanthrone JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens