Title : Autocatalytic modification of the prosthetic heme of horseradish but not lactoperoxidase by thiocyanate oxidation products. A role for heme-protein covalent cross-linking.

Pub. Date : 2005 Nov 16

PMID : 16277530






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The mammalian peroxidases eosinophil peroxidase, lactoperoxidase (LPO), and myeloperoxidase oxidize thiocyanate to the antimicrobial agents hypothiocyanous acid (HOSCN) and (SCN)2 and are part of a defense system that protects the host from infections. thiocyanate myeloperoxidase Homo sapiens