Pub. Date : 1992 Jun 22
PMID : 1627617
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterization of a bile salt-dependent cholesteryl ester hydrolase activity secreted from HepG2 cells. | Bile Acids and Salts | carboxylesterase 1 | Homo sapiens |
| 2 | Although bile salt-dependent CEH activity was measured in the medium at 6 to 96 h (up to 4500 pmol/h per mg cell protein), there was very little activity detected in the corresponding cell homogenates (less than 70 pmol/h per mg cell protein). | Bile Acids and Salts | carboxylesterase 1 | Homo sapiens |
| 3 | Incubation of HepG2 cells with brefeldin A resulted in an 80 to 90% inhibition of secretion of the bile salt-dependent CEH activity, while only inhibiting total protein secretion by 42%. | Bile Acids and Salts | carboxylesterase 1 | Homo sapiens |