Title : Time course characterization of the induction of cytochrome P-450 2E1 by pyrazole and 4-methylpyrazole.

Pub. Date : 1992 Jul 21

PMID : 1627587






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A single treatment with 4-methylpyrazole increased P-450 2B1/B2 levels and oxidation of pentoxyresorufin about 2- to 3-fold. Fomepizole immunoglobulin kappa variable 5-2 Homo sapiens
2 Although significant, the induction of 2B1/B2 by 4-methylpyrazole is more than an order of magnitude less than that by phenobarbital. Fomepizole immunoglobulin kappa variable 5-2 Homo sapiens