Title : Morphine induces CD4+ T cell IL-4 expression through an adenylyl cyclase mechanism independent of the protein kinase A pathway.

Pub. Date : 2005 Nov 15

PMID : 16272288






1 Functional Relationships(s)
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1 We also demonstrate that chronic morphine treatment increases anti-CD3/CD28 Ab-induced IL-4 promoter activity and IL-4 immunoprotein expression through a p38 MAPK-dependent, but protein kinase A- and Erk1/Erk2-independent, mechanism. Morphine mitogen-activated protein kinase 3 Homo sapiens