Pub. Date : 2005 Nov 15
PMID : 16271621
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenite enhances tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1. | arsenite | tumor necrosis factor | Homo sapiens |
| 2 | Our study demonstrated that arsenite pretreatment potentiated the TNF-alpha-induced VCAM-1 expression with up-regulations of both activator protein-1 (AP-1) and nuclear factor-kappaB (NF-kappaB). | arsenite | tumor necrosis factor | Homo sapiens |
| 3 | Our investigation revealed that, by depleting GSH, arsenite attenuated the TNF-alpha-induced VCAM-1 expression as well as a potentiation of AP-1 and an attenuation of NF-kappaB activations by TNF-alpha. | arsenite | tumor necrosis factor | Homo sapiens |
| 4 | Our investigation revealed that, by depleting GSH, arsenite attenuated the TNF-alpha-induced VCAM-1 expression as well as a potentiation of AP-1 and an attenuation of NF-kappaB activations by TNF-alpha. | arsenite | tumor necrosis factor | Homo sapiens |
| 5 | In summary, we demonstrate that arsenite enhances the TNF-alpha-induced VCAM-1 expression in HUVECs via regulation of AP-1 and NF-kappaB activities in a GSH-sensitive manner. | arsenite | tumor necrosis factor | Homo sapiens |