Title : Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease.

Pub. Date : 2005 Nov 15

PMID : 16260738






1 Functional Relationships(s)
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1 Spinal and bulbar muscular atrophy (SBMA) is an adult-onset motor neuron disease caused by the expansion of a trinucleotide CAG repeat encoding the polyglutamine tract in the first exon of the androgen receptor gene (AR). polyglutamine androgen receptor Mus musculus