Title : Multiple eicosanoid-activated nonselective cation channels regulate B-lymphocyte adhesion to integrin ligands.

Pub. Date : 2006 Mar

PMID : 16251477






2 Functional Relationships(s)
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1 We previously found that mechanical strain generated by subjecting lymphocytes to hypotonic challenge triggered AA production and that two CYP450 products of AA, 5,6-epoxyeicosatrienoic acid (5,6-EET) and 20-hydroxyeicosatetraenoic acid (20-HETE), as well as a product of LOX, 5-(S)-hydroperoxyeicosatetrenoic acid (5-HPETE), induced Ca(2+) entry into primary B cells. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 We previously found that mechanical strain generated by subjecting lymphocytes to hypotonic challenge triggered AA production and that two CYP450 products of AA, 5,6-epoxyeicosatrienoic acid (5,6-EET) and 20-hydroxyeicosatetraenoic acid (20-HETE), as well as a product of LOX, 5-(S)-hydroperoxyeicosatetrenoic acid (5-HPETE), induced Ca(2+) entry into primary B cells. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily F member 3 Homo sapiens