Title : TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.

Pub. Date : 2005 Dec 1

PMID : 16251197






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Here, we show that endogenous and overexpressed TAB2, TRAF6 and TAK1 co-immunoprecipitated with Edaradd in 293 cells. edaradd LOC222344 Homo sapiens
2 Moreover, we show that dominant negative forms of TAB2, TRAF6 and TAK1 blocked the NF-kappaB activation induced by Edaradd. edaradd LOC222344 Homo sapiens