Title : In vivo and in vitro effects of simvastatin on inflammatory markers in pre-dialysis patients.

Pub. Date : 2006 Feb

PMID : 16249194






1 Functional Relationships(s)
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1 In the in vitro studies, the average value for cell-associated IL-6 and IL-8 was higher in CKD (155+/-95 pg/ml monocytes for IL-6 and 722+/-921 pg/ml monocytes for IL-8) vs HS (137+/-87 pg/ml monocytes and 186+/-125 pg/ml monocytes) (P<0.01) and was not affected by simvastatin alone. Simvastatin C-X-C motif chemokine ligand 8 Homo sapiens