Pub. Date : 2005
PMID : 16244377
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A commonly used NBV, glyceryl trinitrate (GTN) is bioactivated by mitochondrial, class 2 aldehyde dehydrogenase (ALDH2). | Nitroglycerin | aldehyde dehydrogenase 2 family member | Rattus norvegicus |
| 2 | A commonly used NBV, glyceryl trinitrate (GTN) is bioactivated by mitochondrial, class 2 aldehyde dehydrogenase (ALDH2). | Nitroglycerin | aldehyde dehydrogenase 2 family member | Rattus norvegicus |
| 3 | The GTN bioactivation step, however, inac-tivates ALDH2 and may alter the metabolism of these aldehydes. | Nitroglycerin | aldehyde dehydrogenase 2 family member | Rattus norvegicus |
| 4 | GTN (1 microM) inhibited ALDH2 activity (55 +/- 6% of control) and ablated ALDH3 activity. | Nitroglycerin | aldehyde dehydrogenase 2 family member | Rattus norvegicus |