Title : Metamizole-furosemide interaction study in healthy volunteers.

Pub. Date : 1992

PMID : 1623899






1 Functional Relationships(s)
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1 Metamizole significantly reduced furosemide clearance (175 vs 141 ml.min-1), furosemide-stimulated plasma renin activity (1.42 vs 0.79 ng AI.ml-1.h-1) and the urinary excretion of prostacyclin metabolites and of prostaglandin F2 alpha (by 70-81%). Furosemide renin Homo sapiens