Title : P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1.

Pub. Date : 2006 Aug

PMID : 16236484






1 Functional Relationships(s)
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1 Treatment of cells with the Ca2+ chelator BAPTA-AM and inhibition of Src and PLD2 with PP2 or 1-butanol, respectively, abrogated P2Y12 receptor-mediated activation of Rap1 and PKB. 1-Butanol phospholipase D2 Homo sapiens