Title : Down-regulation of integrin alpha2 surface expression by mutant epidermal growth factor receptor (EGFRvIII) induces aberrant cell spreading and focal adhesion formation.

Pub. Date : 2005 Oct 15

PMID : 16230389






1 Functional Relationships(s)
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Protein Name
Organism
1 Inhibition of EGFRvIII catalytic activity using the EGFR-selective tyrphostin AG1478 restored integrin alpha2 expression within 4 to 8 hours after treatment. Tyrphostins epidermal growth factor receptor Homo sapiens