Title : A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT.

Pub. Date : 2005 Nov 4

PMID : 16227782






1 Functional Relationships(s)
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1 At physiological nucleotide concentrations, excision of ZDV, carbovir (the active metabolite of abacavir; ABC), stavudine (d4T), and tenofovir was further decreased, while excision of didanosine (ddI), zalcitabine (ddC), lamivudine (3TC), and emtricitabine (FTC) was unchanged. abacavir ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens