Title : 5-Hydroxytryptamine 1A receptor blockade facilitates aversive learning in mice: interactions with cholinergic and glutamatergic mechanisms.

Pub. Date : 2006 Feb

PMID : 16223872






2 Functional Relationships(s)
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1 1) Pretraining administration of the 5-HT(1A) receptor agonist 8-OH-DPAT [8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide] facilitated PA retention at low doses (0.01 and 0.03 mg/kg) but impaired PA retention at higher doses (0.1-1.0 mg/kg), consistent with previous findings in the rat. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
2 1) Pretraining administration of the 5-HT(1A) receptor agonist 8-OH-DPAT [8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide] facilitated PA retention at low doses (0.01 and 0.03 mg/kg) but impaired PA retention at higher doses (0.1-1.0 mg/kg), consistent with previous findings in the rat. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus