Title : Investigation of the binding determinants of phosphopeptides targeted to the SRC homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor.

Pub. Date : 2005 Oct 20

PMID : 16220982






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Of the amino acids tested, leucine provided the highest affinity at pY+1 and its main chain NH is involved with a hydrogen bond with Stat3, presumably Ser636. Leucine signal transducer and activator of transcription 3 Homo sapiens