Title : [Intervention of cetirizine on monocyte chemoattractant protein-1 in cutaneous inflammation].

Pub. Date : 2005 May

PMID : 16220783






2 Functional Relationships(s)
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1 RESULTS: Compared with the control group of dermal fibroblast (DF) cells and HaCaT cells, MCP-1 mRNA was significantly upregulated by histamine (10 micromol x L(-1)) and IFN-gamma (20 ng x mL(-1)). Histamine C-C motif chemokine ligand 2 Homo sapiens
2 The enhancing effects of histamine and IFN-gamma on MCP-1 protein production were significantly inhibited by cetirizine (1 and 10 micromol x L(-1)) in DF and HaCaT cells. Histamine C-C motif chemokine ligand 2 Homo sapiens