Title : Antioxidant and nitric oxide-sparing actions of dihydropyridines and ACE inhibitors differ in human endothelial cells.

Pub. Date : 2006

PMID : 16220025






2 Functional Relationships(s)
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1 The DHP Ca2+-channel agonist BayK8644 and ACE inhibitors captopril and ramiprilat led extracellular superoxide concentration to control level. ramiprilat angiotensin I converting enzyme Homo sapiens
2 Suppression of substance P-evoked NO release by Ang II (>70%, n = 6) was reversed by the PKC inhibitor chelerythrine, the DHP amlodipine and nisoldipine and the ACE inhibitor ramiprilat. ramiprilat angiotensin I converting enzyme Homo sapiens