Pub. Date : 2005 Oct 30
PMID : 16219424
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with either Y27632 (1 microM) or C3 toxin (10 microg/ml) significantly inhibited the nicotine-induced increase of tyrosine hydroxylase (TH) mRNA and the corresponding enzyme activity. | Nicotine | tyrosine hydroxylase | Rattus norvegicus |
| 2 | Treatment with either Y27632 (1 microM) or C3 toxin (10 microg/ml) significantly inhibited the nicotine-induced increase of tyrosine hydroxylase (TH) mRNA and the corresponding enzyme activity. | Nicotine | tyrosine hydroxylase | Rattus norvegicus |
| 3 | Y27632 significantly inhibited nicotine-induced phosphorylation of TH at Ser40 as well as Ser19, which are known to be phosphorylated by Ca(2+)/calmodulin kinase II. | Nicotine | tyrosine hydroxylase | Rattus norvegicus |
| 4 | Furthermore, Y27632 (10 microM) as well as C3 toxin (10 microg/ml) significantly inhibited the nicotine-induced increase of TH at the protein level. | Nicotine | tyrosine hydroxylase | Rattus norvegicus |