Title : Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon.

Pub. Date : 2005 Dec 9

PMID : 16216880






1 Functional Relationships(s)
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1 14-3-3epsilon overexpression also increased insulin-stimulated insulin receptor and IRS-1 tyrosine phosphorylation, followed by increased activation of Raf1, ERK1/2, and Akt/protein kinase B. Insulin-induced glycogen synthase activity and thymidine incorporation were also augmented. Thymidine tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide Mus musculus