Title : Dopamine transporter availability in medication free and in bupropion treated depression: a 99mTc-TRODAT-1 SPECT study.

Pub. Date : 2005 Dec

PMID : 16213028






6 Functional Relationships(s)
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1 Dopamine transporter availability in medication free and in bupropion treated depression: a 99mTc-TRODAT-1 SPECT study. Bupropion solute carrier family 6 member 3 Homo sapiens
2 BACKGROUND: Bupropion is thought to exert its antidepressive effect by blocking the dopamine transporter (DAT). Bupropion solute carrier family 6 member 3 Homo sapiens
3 BACKGROUND: Bupropion is thought to exert its antidepressive effect by blocking the dopamine transporter (DAT). Bupropion solute carrier family 6 member 3 Homo sapiens
4 The purpose of this study was to evaluate the DAT activity in depressed patients by means of 99mTc-TRODAT-1 SPECT in relation to the efficacy of bupropion treatment. Bupropion solute carrier family 6 member 3 Homo sapiens
5 The average DAT occupancy due to the bupropion treatment was 20.84+/-27.7%. Bupropion solute carrier family 6 member 3 Homo sapiens
6 CONCLUSIONS: In good agreement with other PET studies, we found 20.84% DAT occupancy during bupropion treatment. Bupropion solute carrier family 6 member 3 Homo sapiens