Title : Prevention of acute lung allograft rejection in rat by the janus kinase 3 inhibitor, tyrphostin AG490.

Pub. Date : 2005 Oct

PMID : 16210130






1 Functional Relationships(s)
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1 BACKGROUND: Tyrphostin AG490 (AG490) potently and selectively inhibits gammac/Janus kinase 3-dependent signaling pathways, including downstream Stat5a/b activation and subsequent T cell proliferation by alloantigen stimulation. Tyrphostins Janus kinase 3 Rattus norvegicus