Title : Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart.

Pub. Date : 2005 Oct

PMID : 16202860






1 Functional Relationships(s)
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1 Although phVEGF-A165 upregulated (P < .0001) mVEGFR-2, addition of candesartan downregulated endogenous mVEGF-A (P < .0001) and mVEGFR-2 (P < .0001) below the level in normal myocardium. candesartan vascular endothelial growth factor A Mus musculus