Title : JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells.

Pub. Date : 2006 Apr

PMID : 16202406






1 Functional Relationships(s)
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1 SB202190, PD98059 and doxycycline markedly suppressed the levels of p-JNK-1/p-JNK-2 and/or p-ERK1/p-ERK2, as well as IL-1beta, TNF-alpha and IL-8 mRNAs and proteins stimulated by hyperosmolar media. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one C-X-C motif chemokine ligand 8 Homo sapiens