Title : Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.

Pub. Date : 2005 Nov

PMID : 16200064






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Most notably, by tightly regulating Trp53 knock-down using tetracycline-based systems, we show that cultured mouse fibroblasts can be switched between proliferative and senescent states and that tumors induced by Trp53 suppression and cooperating oncogenes regress upon re-expression of Trp53. Tetracycline transformation related protein 53 Mus musculus
2 Most notably, by tightly regulating Trp53 knock-down using tetracycline-based systems, we show that cultured mouse fibroblasts can be switched between proliferative and senescent states and that tumors induced by Trp53 suppression and cooperating oncogenes regress upon re-expression of Trp53. Tetracycline transformation related protein 53 Mus musculus
3 Most notably, by tightly regulating Trp53 knock-down using tetracycline-based systems, we show that cultured mouse fibroblasts can be switched between proliferative and senescent states and that tumors induced by Trp53 suppression and cooperating oncogenes regress upon re-expression of Trp53. Tetracycline transformation related protein 53 Mus musculus