Title : Identification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes.

Pub. Date : 2005 Jun

PMID : 16192110






2 Functional Relationships(s)
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1 Identification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes. Valsartan cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Although CYP2C9 is involved in valsartan metabolism, CYP-mediated drug-drug interaction between valsartan and other co-administered drugs would be negligible. Valsartan cytochrome P450 family 4 subfamily F member 3 Homo sapiens