Title : Variolin B and its derivate deoxy-variolin B: new marine natural compounds with cyclin-dependent kinase inhibitor activity.

Pub. Date : 2005 Oct

PMID : 16181779






1 Functional Relationships(s)
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1 In conclusion, these variolins are a new class of CDK inhibitors that activate apoptosis in a p53-independent fashion and thus they may be effective against tumours with p53 mutations or deletions. variolins cyclin dependent kinase 1 Homo sapiens