Title : The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials.

Pub. Date : 2005 Aug

PMID : 16179524






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In a rat cerebral artery occlusion model of stroke, postinsult treatment with lithium or valproate reduces ischemia-induced brain infarction, caspase-3 activation, and neurological deficits, and these neuroprotective effects are associated with HSP70 upregulation and, in the case of valproate, HDAC inhibition. Valproic Acid caspase 3 Rattus norvegicus