Title : Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies.

Pub. Date : 2005 Nov 1

PMID : 16178003






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Proteasome inhibition with bortezomib has specifically promoted apoptosis of tumor cells through the stabilization of p53, p21, p27, Bax, and IkappaBalpha, resulting in nuclear factor kappaB inhibition. Bortezomib tumor protein p53 Homo sapiens