Title : Signal transduction mechanisms involved in the proliferation of C6 glioma cells induced by lysophosphatidic acid.

Pub. Date : 2005 May

PMID : 16176063






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LPA induced transient (10 min) phosphorylations of ERK 1/2, Akt and the transcription factor CREB. lysophosphatidic acid mitogen activated protein kinase 3 Rattus norvegicus
2 The LPA-induced phosphorylation of ERK 1/2 and CREB was blocked by inhibition of PI3K, PKC and MEK, but that of Akt was only inhibited by wortmannin, the PI3K inhibitor. lysophosphatidic acid mitogen activated protein kinase 3 Rattus norvegicus