Title : Cyclooxygenase-independent down-regulation of multidrug resistance-associated protein-1 expression by celecoxib in human lung cancer cells.

Pub. Date : 2005 Sep

PMID : 16170027






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The COX-2 inhibitor celecoxib down-regulated the expression of MRP1 protein in A549 cells, which was accompanied by increased accumulation and enhanced cytotoxicity of doxorubicin, an MRP1 substrate. Doxorubicin ATP binding cassette subfamily C member 1 Homo sapiens
2 The COX-2 inhibitor celecoxib down-regulated the expression of MRP1 protein in A549 cells, which was accompanied by increased accumulation and enhanced cytotoxicity of doxorubicin, an MRP1 substrate. Doxorubicin ATP binding cassette subfamily C member 1 Homo sapiens