Title : Liver injury and changes in hepatitis C Virus (HCV) RNA load associated with protease inhibitor-based antiretroviral therapy for treatment-naive HCV-HIV-coinfected patients: lopinavir-ritonavir versus nelfinavir.

Pub. Date : 2005 Oct 15

PMID : 16163639






2 Functional Relationships(s)
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1 The mean ALT level increased by 45 U/L at 24 weeks and 18 U/L at 48 weeks in the nelfinavir group but decreased by 18 U/L at 24 weeks and 7 U/L at 48 weeks in the lopinavir-ritonavir group. Nelfinavir glutamic pyruvic transaminase, soluble Mus musculus
2 Eight patients in the nelfinavir group and 2 patients in the lopinavir-ritonavir group had grade 3 or 4 flares in the ALT level. Nelfinavir glutamic pyruvic transaminase, soluble Mus musculus