Title : c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats.

Pub. Date : 2005 Oct

PMID : 16157790






2 Functional Relationships(s)
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1 The NADPH oxidase activity increase, collagen synthesis, c-Src, and MAP kinase phosphorylation induced by aldosterone were significantly reduced by eplerenone (selective mineralocorticoid receptor blocker) and PP2 (selective c-Src inhibitor). Eplerenone SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus
2 The NADPH oxidase activity increase, collagen synthesis, c-Src, and MAP kinase phosphorylation induced by aldosterone were significantly reduced by eplerenone (selective mineralocorticoid receptor blocker) and PP2 (selective c-Src inhibitor). Eplerenone SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus