Title : Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control.

Pub. Date : 2005 Sep 12

PMID : 16157703






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Three different strategies to decrease the guanine nucleotide exchange function of eIF2B all inhibit eIF2 shuttling into the foci. Guanine Nucleotides eukaryotic translation initiation factor 2B subunit delta Homo sapiens
2 These results implicate a defined cytoplasmic center of eIF2B in the exchange of guanine nucleotides on the eIF2 translation initiation factor. Guanine Nucleotides eukaryotic translation initiation factor 2B subunit delta Homo sapiens
3 A focused core of eIF2B guanine nucleotide exchange might allow either greater activity or control of this elementary conserved step in the translation pathway. Guanine Nucleotides eukaryotic translation initiation factor 2B subunit delta Homo sapiens