Pub. Date : 2005 Oct 1
PMID : 16157201
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quantitative molecular monitoring of BCR-ABL and MDR1 transcripts in patients with chronic myeloid leukemia during Imatinib treatment. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Different mechanisms could sustain Imatinib resistance, including overexpression of MDR1, a gene already known to be responsible for multidrug resistance in other hematologic malignancies. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Reported data maintain that MDR1 expression would play an important role in Imatinib resistance when the disease is not fully controlled (e.g., progressive disease or during the first months of treatment). | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |