Title : The Evi1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity.

Pub. Date : 2005 Sep

PMID : 16156860






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 TPA-stimulated HEL cells normally undergo: (1) growth arrest; (2) altered morphology; (3) endomitosis and (4) characteristic changes in gene expression, including reduction of the erythroid-specific glycophoryn A and elevation of the specific glycoproteins GPIIIa and GPVI. Tetradecanoylphorbol Acetate integrin subunit beta 3 Homo sapiens
2 Evi1-expressing, TPA-treated HEL cells still showed growth arrest, had reduced and enhanced glycophoryn A and GPIIIa mRNA"s, respectively, but failed to significantly elevate GPVI mRNA. Tetradecanoylphorbol Acetate integrin subunit beta 3 Homo sapiens