Pub. Date : 2005 Nov 1
PMID : 16153839
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An SAR study around the mixed 5-HT1ABD receptor antagonist SB-272183 found that introduction of cis-2,6-dimethyl substitution onto the piperazine ring was a key structural change, which imparted a combination of both excellent selectivity over the 5-HT1A and 5-HT1D receptors and low intrinsic activity. | Piperazine | 5-hydroxytryptamine receptor 1A | Homo sapiens |