Title : Cyclooxygenase-1 haplotype modulates platelet response to aspirin.

Pub. Date : 2005 Oct

PMID : 16150050






1 Functional Relationships(s)
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1 BACKGROUND: Aspirin (acetylsalicylic acid) irreversibly inhibits platelet cyclooxygenase (COX)-1, the enzyme that converts arachidonic acid (AA) to the potent platelet agonist thromboxane (TX) A2. Arachidonic Acid mitochondrially encoded cytochrome c oxidase I Homo sapiens