Title : 2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) exhibits p53-dependent and -independent antiproliferative activity in human nasopharyngeal carcinoma cells in vitro and in vivo.

Pub. Date : 2005 Oct

PMID : 16142332






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Upregulation of p53, phosphorylated p53 at Ser15 and biochemical markers for apoptosis, such as cleaved caspase-3, cleaved caspase-7 and cleaved PARP, were observed in SarCNU-treated HK-1 but not CNE-2 cells. 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide collagen type XI alpha 2 chain Homo sapiens