Title : The phosphorylation of Ser318 of insulin receptor substrate 1 is not per se inhibitory in skeletal muscle cells but is necessary to trigger the attenuation of the insulin-stimulated signal.

Pub. Date : 2005 Nov 11

PMID : 16129678






1 Functional Relationships(s)
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1 The Ser/Thr phosphorylation of insulin receptor substrate 1 (IRS) is one key mechanism to stimulate and/or attenuate insulin signal transduction. Threonine insulin Homo sapiens