Title : Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954.

Pub. Date : 2005 Oct 14

PMID : 16129418






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The complex structure indicates the essentiality of the two nitro groups: one nitro group forms hydrogen bonds with the side-chain of Asn161 of QR2 to hold the other nitro group in position for the reduction. nitro N-ribosyldihydronicotinamide:quinone reductase 2 Homo sapiens
2 The complex structure indicates the essentiality of the two nitro groups: one nitro group forms hydrogen bonds with the side-chain of Asn161 of QR2 to hold the other nitro group in position for the reduction. nitro N-ribosyldihydronicotinamide:quinone reductase 2 Homo sapiens
3 The complex structure indicates the essentiality of the two nitro groups: one nitro group forms hydrogen bonds with the side-chain of Asn161 of QR2 to hold the other nitro group in position for the reduction. nitro N-ribosyldihydronicotinamide:quinone reductase 2 Homo sapiens