Title : p53 Gene status and response to topotecan-containing chemotherapy in advanced ovarian carcinoma.

Pub. Date : 2005

PMID : 16127286






1 Functional Relationships(s)
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1 Although untreated mutant p53 tumors may be responsive to first-line paclitaxel-containing therapy, it is likely that loss of p53 leads to genomic instability resulting in rapid progression to drug resistance. Paclitaxel tumor protein p53 Homo sapiens