Title : Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

Pub. Date : 2005 Oct 21

PMID : 16123044






1 Functional Relationships(s)
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1 In this regard, it has been recently observed that the prolyl isomerase Pin1 can interact with proteins phosphorylated on serine or threonine residues that precede prolines (pS/T-P), such as the transcription factors p53 and c-Jun, thereby controlling their activity by promoting the cis-trans isomerization of these pS/T-P bonds. Proline peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens